Here's what to know about the unusually erratic and damaging weather.
Monday forecast
Forecasters warned of dangerous winds from Florida all the way north to New Jersey, while heavy rain was likely across New York and New England.
A tornado watch was in effect until early Monday for a large swath of North Carolina and Virginia, with gusts potentially reaching 70 mph and possible hail the size of ping pong balls, according to the National Weather Service office in Blacksburg, Virginia.
The massive storm that began Friday earned an unusual "high risk" designation from meteorologists. Still, experts said it's not unusual to see such weather extremes in March.
Multiple tornadoes in several states
In Tylertown, Mississippi, tornadoes ripped tall trees in half and wiped out entire neighborhoods. Six people were killed and more than 200 were displaced, Gov. Tate Reeves said.
Hailey Hart and her fiancé Steve Romero hunkered down with their three huskies inside their 1994 Toyota Celica as a twister ripped apart their home Saturday. Romero said he prayed out loud and hugged Hart as the car rolled onto its side, windows shattering, before it landed on its wheels again.
“It was a bad dream come true,” Romero said. The couple escaped with only scratches.
Wayne County, Missouri, resident Dakota Henderson said he and others rescuing trapped neighbors found five bodies scattered in rubble outside what remained of his aunt’s house. Scattered twisters killed at least a dozen people in the state Friday, authorities said.
Coroner Jim Akers of Butler County, Missouri, described the home where one man was killed as “just a debris field.”
“The floor was upside down,” he said. “We were walking on walls.”
Wildfires and dust storms also proved deadly
Wind-driven wildfires caused extensive damage in Texas and Oklahoma and officials warned that parts of both states would again face an increased risk of fire danger in the coming week.
More than 130 fires were reported across Oklahoma and nearly 400 homes were damaged or destroyed, Gov. Kevin Stitt said.
“Nobody has enough resources to fight fires when the wind is blowing 70 mph,” said Terry Essary, the fire chief of Stillwater, Oklahoma. “It’s an insurmountable task.”
Oklahoma Department of Emergency Management spokesperson Keli Cain said Sunday that two people were killed as a result of the wildfires and weather.
Meanwhile, dust storms spurred by high winds claimed almost a dozen lives on Friday. Eight people died in a Kansas highway pileup involving at least 50 vehicles, according to the state highway patrol. Authorities said three people also were killed in car crashes during a dust storm in Amarillo, in the Texas Panhandle.
Refuge and recovery efforts
President Donald Trump said the White House was monitoring the storms and would assist state and local officials to help in the recovery. He said National Guard troops were deployed to Arkansas, where officials confirmed three deaths.
“Please join Melania and me in praying for everyone impacted by these terrible storms!” Trump posted on his social media network on Sunday.
At least three people, including an 82-year-old woman, were killed in central Alabama when multiple tornadoes swept across the state.
In Troy, Alabama, parks officials said the recreation center where many residents had taken refuge had to be closed due to damage from overnight storms. No one was injured.
“We are thankful the Lord provided protection over our community, and over 200 guests at the Recreation Center storm shelter on Saturday night,” the parks department said in a statement.
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